Infectious Burden and Cognitive Decline in the Northern Manhattan Study
نویسندگان
چکیده
منابع مشابه
Infectious Burden and Cognitive Decline in the Northern Manhattan Study.
OBJECTIVES To determine whether infectious burden (IB) is associated with worse performance and decline on a battery of neuropsychological tests. DESIGN Prospective cohort study (Northern Manhattan Study (NOMAS)). SETTING Community. PARTICIPANTS A subsample of 588 stroke-free NOMAS participants with IB and cognitive data (mean age 71 ± 8, 62% female, 14% white, 16% black, 70% Hispanic) an...
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OBJECTIVE To determine the association between a composite measure of serological test results for common infections (Chlamydia pneumoniae, Helicobacter pylori, cytomegalovirus, and herpes simplex virus 1 and 2) and stroke risk in a prospective cohort study. DESIGN Prospective cohort followed up longitudinally for median 8 years. SETTING Northern Manhattan Study. Patients Randomly selected ...
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BACKGROUND AND PURPOSE The overall burden of prior infections may contribute to atherosclerosis and stroke risk. We hypothesized that serological evidence of common infections would be associated with carotid plaque thickness in a multiethnic cohort. METHODS Antibody titers to 5 common infectious microorganisms (ie, Chlamydia pneumoniae, Helicobacter pylori, cytomegalovirus, and herpesvirus 1...
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BACKGROUND Moderate alcohol intake may slow cognitive decline, and both vascular and neurodegenerative mechanisms have been implicated. METHODS We examined reported alcohol intake and cognitive decline in a community-based cohort of Hispanic, black and white individuals (n = 1,428). The role of the apolipoprotein E epsilon4 (APOE4) allele as a modifier was also studied. RESULTS AND CONCLUSI...
متن کاملLeisure-time physical activity associates with cognitive decline: The Northern Manhattan Study.
OBJECTIVE Because leisure-time physical activity (LTPA) is protective against incident dementia, we hypothesized that LTPA is protective against decline in domain-specific cognitive performance. METHODS As part of the Northern Manhattan Study, LTPA was ascertained at enrollment using a validated in-person questionnaire. We assessed cognition in participants in the Northern Manhattan Study MRI...
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ژورنال
عنوان ژورنال: Journal of the American Geriatrics Society
سال: 2015
ISSN: 0002-8614
DOI: 10.1111/jgs.13557